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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK10
All Species:
33.03
Human Site:
Y188
Identified Species:
60.56
UniProt:
Q15131
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15131
NP_001092003.2
360
41038
Y188
D
F
G
L
A
R
A
Y
G
V
P
V
K
P
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546775
360
41038
Y188
D
F
G
L
A
R
A
Y
S
I
P
M
K
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMM4
360
40942
Y188
D
F
G
L
A
R
A
Y
G
V
P
V
K
P
M
Rat
Rattus norvegicus
Q4KM47
358
40615
Y186
D
F
G
L
A
R
A
Y
G
V
P
V
K
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001103409
370
41951
Y196
D
F
G
L
A
R
T
Y
G
M
P
P
Q
P
M
Frog
Xenopus laevis
P23437
297
33852
L134
D
L
K
P
Q
N
L
L
I
N
S
D
G
A
I
Zebra Danio
Brachydanio rerio
NP_001017622
275
30997
E112
V
V
V
G
S
H
L
E
S
L
F
L
V
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPC0
952
108820
Y710
D
F
G
L
A
R
E
Y
G
S
P
I
K
K
Y
Honey Bee
Apis mellifera
XP_392973
410
46389
F214
D
F
G
L
A
R
W
F
G
L
P
L
K
P
M
Nematode Worm
Caenorhab. elegans
Q09437
719
83549
Y509
D
F
G
L
A
R
E
Y
G
D
P
L
K
K
F
Sea Urchin
Strong. purpuratus
XP_783449
397
44907
Y208
D
F
G
L
A
R
R
Y
G
L
P
V
R
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
Y189
D
F
G
L
A
R
S
Y
S
H
D
H
T
G
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
Y182
D
F
G
L
A
R
H
Y
E
G
D
I
P
Q
P
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93
N.A.
96.9
90.5
N.A.
N.A.
82.9
36.9
60.8
N.A.
21.3
63.9
25.8
63.7
Protein Similarity:
100
N.A.
N.A.
96.9
N.A.
98.8
93.6
N.A.
N.A.
89.7
53.6
69.1
N.A.
27.8
73.6
36.4
75.8
P-Site Identity:
100
N.A.
N.A.
80
N.A.
100
100
N.A.
N.A.
73.3
6.6
0
N.A.
66.6
73.3
66.6
80
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
N.A.
86.6
13.3
20
N.A.
73.3
93.3
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.4
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
45.5
N.A.
43.6
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
85
0
31
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
93
0
0
0
0
0
0
0
0
8
16
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
16
8
8
0
0
0
0
0
0
% E
% Phe:
0
85
0
0
0
0
0
8
0
0
8
0
0
0
8
% F
% Gly:
0
0
85
8
0
0
0
0
62
8
0
0
8
8
0
% G
% His:
0
0
0
0
0
8
8
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
8
0
16
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
54
16
0
% K
% Leu:
0
8
0
85
0
0
16
8
0
24
0
24
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
54
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
70
8
8
54
8
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
85
8
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
8
0
8
0
24
8
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% T
% Val:
8
8
8
0
0
0
0
0
0
24
0
31
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _